Effect of p ,p′-DDT, o ,p′-DDT and p ,p′-DDE on the Reproductive Performance of Caged White Leghorns
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چکیده
منابع مشابه
Reductive metabolism of p,p'-DDT and o,p'-DDT by rat liver cytochrome P450.
The in vitro metabolism of p,p'-DDT [1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane], an important environmental pollutant, was examined in rat liver, focusing on reductive dechlorination. When p,p'-DDT was incubated with liver microsomes of rats in the presence of NADPH or NADH, a dechlorinated metabolite, p,p'-DDD [1,1-dichloro-2,2-bis(4-chlorophenyl)ethane], was formed under anaerobic conditi...
متن کاملTranscriptional effects of Organochlorine o,p′-DDT and its Metabolite p,p′-DDE in Transfected MDA-MB 231 and MCF-7 Breast Cancer Cell Lines
Background: The organochlorine DDT has estrogenic activity but the mechanism underlying the estrogenic activity of this pesticide remains unclear. In the present investigation here, we studied the transcriptional effects of a synthetic organochlorine pesticide o,p’-DDT [1.1.1.-trichloro-2-(o-chlorophenyl)-2-p-chloriphenyl ethane] and its metabolite p,p'-DDE (2-2-bis(4/chlorophenyl)-1-1-di...
متن کاملDirect effect of p,p'-DDT on mice liver
Contact with the pesticide dichlorodiphenyltrichloroethane (p,p′-DDT) can be the cause of various harmful effects in humans, wildlife, and the environment. This pesticide is known to be persistent, lipophilic, resistant to degradation, and bioaccumulive in the environment and to be slowly released into bloodstream. Growing evidence shows that exposure to DDT is linked to type 2 diabetes mellitu...
متن کاملNonoccupational determinants of plasma DDT and p,p'-DDE in men from Chiapas, Mexico.
A cross-sectional study was conducted to evaluate nonoccupational biological exposure to 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (DDT) compounds and to identify the main factors associated with such exposure in a malaria endemic region in Mexico. Capillary gas column chromatography was used to determine levels of p,p'-DDT and its metabolites in plasma. The mean age of the 144 male partici...
متن کاملAnalyses of lindane, vinclozolin, aldrin, p,p'-DDE, o,p'-DDT and p,p'-DDT in human serum using gas chromatography with electron capture detection and tandem mass spectrometry.
A sensitive, selective and reliable procedure was developed and validated to determine organochlorinated compounds, which present endocrine-disrupting effects, lindane, vinclozolin, aldrin, p,p'-DDT, o,p'-DDT and p,p'-DDE, in human serum. The analytical methodology combines serum extraction with organic solvents, clean-up of the organic extract using acid treatment with H2SO4, elution of the cl...
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ژورنال
عنوان ژورنال: Poultry Science
سال: 1972
ISSN: 0032-5791
DOI: 10.3382/ps.0510122